Association between Effect Ofsome Pro-inflammatory and Anti-inflammatory Cytokines before and After Surgical Patients
نویسندگان
چکیده
The aims of our study were to investigate association some effect pro- inflammatory and antiinflammatory cytokines before after surgical patients through serum concentration of, TNF-?,IL-2, IL-4, IL-6, IL-10. 35 blood samples collected from (17 male, 18 female)withgeneral anesthesia Al-Diwaniyah Hospital, Iraq. Samples taken surgery (Tpre), the firstday) T1), third day) T3 (and fifth day (T5) operative skin incision.Pro-inflammatory cytokines(IL-2, TNF-?) anti-inflammatory (IL-4, IL-10) quantitatively analyzed byELISA technique.Our resultsshowed there no significant difference (p<0.05) in WBCs count, WBCspercentage (neutrophil, eosinophil, basophil, monocytes lymphocytes), PCV, PCT percentage HBconcentration (Tpre) (T1, T3, T5) operation. Also results showed therewere a decrease IL-2 (T1) (T3) postoperative comparedwith (T pre), returned pre-operative values on (T5). IL-6 increase first daypostoperative (T1), then decreased (T3 compared TNF? slightly increasedin (T1 but didn’t significantly, IL-4 show any betweenTpre, T1, T5. IL-10 with tothe preoperative We could be concludethe pro? anti?inflammatory cytokinesbalanced ratio is essential regulate responses postoperative. Anti-inflammatory cytokine(IL-10) increased suppress excessive pro-inflammatory cytokine (IL-6).
منابع مشابه
Unbalanced Pro-Inflammatory and Anti-Inflammatory Cytokines Ratio and Endometriosis: A Contributive Pathogenic Role?
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ژورنال
عنوان ژورنال: Medico-Legal Update
سال: 2021
ISSN: ['0971-720X', '0974-1283']
DOI: https://doi.org/10.37506/mlu.v21i2.2788